Can Convenia Cause Anemia In Cats

The Convenia package insert notes the potential for cephalosporin-associated myelotoxicity leading to toxic neutropenia. There have been numerous reports of severe myelotoxicity and neutropenia in dogs and cats since the FDA approved the drug. Although not all cases can be directly attributed to cefovecin use, it is important to remember that severe adverse reactions could need prolonged treatment due to cefovecin’s long-lasting activity. Although cefovecin’s long-activity properties are convenient from an administration perspective, it is important to consider the possibility of adverse effects.

I. What is anemia in cats?

Anemia is a decrease in hemoglobin, red blood cells, or both that circulate throughout your cat’s body. Anemia isn’t a disease, but it is often a sign of another condition.

Anemia can be a serious condition in cats that are more lethargic than usual.

Convenia(r), can also lead to anemia, decreased immunity system efficiency, or a problem with blood platelets. Your veterinarian should be contacted immediately if your pet experiences persistent, serious, or worsening adverse effects.

II. II. What are the signs and symptoms of anemia?

Anemia is most commonly seen in the gums. They may appear pale pink or white.

“Pale gums or lethargy are signs that you need to have blood tests done.”

Anemia causes cats to feel tired and sluggish. Anemia can manifest as bloody noses, blood in the stool or urine, and may also cause blood loss. Lethargy and pale gums are signs of blood loss.

III. Convenia for Cats

Contrary to regular antibiotics which are quickly cleared from the body, Convenia remains in the body for up to two months after injection. Even though it only has a two-week antibacterial effect, it is still effective. Side effects are possible with all drugs. Some cats may be able to tolerate Convenia well, while others might experience side effects that can be life-threatening. Convenia is a long-acting drug that can’t be stopped.


Anemia refers to a decrease of red blood cell count due to loss, destruction or insufficient production of red blood cells. There are two types of anemia we can see in feline friends: regenerative and non-regenerative.

1. Regenerative

Regenerative anemia is a condition in which your cat’s bone marrow responds normally to the loss of red blood cells.

Regenerative anemia can be caused by sudden or acute blood loss due to injury, parasites or infection or serious illness (such cancer). This type of anemia is more common in younger cats.

2. Non-Regenerative

Non-regenerative anemia is when a cat’s bone marrow cannot adequately respond to the reduced number of red blood cell.

Most cats with non-regenerative anemia are suffering from kidney disease (renal failure). Your cat’s kidneys produce a hormone that aids in the production of red blood cells if they are healthy. Anemia is when the kidneys stop working properly. This can lead to an inability for the cat to replace red blood cells as fast as it needs them.

This type of anemia is most common in older cats. It could also be caused bone marrow disorders or liver disease.

V. Signs and symptoms of anemia in cats

Anemia is a condition in which your cat has anemia. The severity, duration, and the cause of the illness will determine the symptoms. Anemia is a common condition in cats.

* Lack of energy or lethargy

* A decreased appetite

* Rapid breathing

* Breathing difficulty

* If your cat is suffering from severe illness, you may notice one or more of these symptoms:

* White gums or pale gums

* Weakness

* Higher heart rate

* Jaundice (yellow or stained skin, gums, or eyes).

It is important to see your veterinarian immediately if your cat exhibits any of these symptoms.

VI. VI. What are the other important tests for cats who are anemic?

It is important to determine if there are any signs of a decreased red blood cell count. These new red blood cell will be released early. The immature red cells called reticulocytes can be stained to make it easier to identify on a blood test. Anemia that is responsive to treatment will show up as a higher number of reticulocytes. The majority of automated blood analyzers can detect reticulocytes and help your veterinarian determine if the cat is suffering from anemia.

VII. Safety precautions

Cefovecin sodium is not recommended for use in pets or cats under 4 months of age.

To avoid medication errors, cefovecin salt should be distinguished from injectable cephalosporins and other drugs with similar names. Convenia (maropitant) was mistakenly misidentified by the FDA Center for Veterinary Medicine. Although the error was discovered before the drugs were administered it shows the importance of being aware of the “look-alike, sounds-alike” drug and the possibility of error when administering cefovecin.

VIII. How can anemia be treated?

A blood transfusion may be necessary if your cat has severe anemia. Blood samples will be taken to diagnose the problem or for blood typing. A blood transfusion serves to stabilize your cat, while diagnosing the cause of anemia and allowing for other treatment options to begin.

IX. Drug Interactions

Cefovecin sodium, which is high protein-bound (98.5% for dogs and 99.8% for cats), can result in high active (free) concentrations of cefovecin and other drugs when given concurrently with other highly-protein-bound drugs. In vitro experiments have shown that cefovecin sodium can increase the free concentrations (active) of carprofen, furosemide and ketoconazole when administered concurrently. However, this is not clinically relevant and it is highly unlikely that cefovecin and carprofen will interact.

Fluoroquinolones not only have been shown to work well with cephalosporins but are also effective against Pseudomonas. It has yet to be studied whether fluoroquinolones can be used in combination with cefovecin.

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